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Clinical Gastroenterology and Hepatology Research is an international, peer-reviewed, open-access journal dedicated to publishing the most recent advances in Gastroenterology and Hepatology Research. Researchers and practitioners participate in JCGHR to discuss the latest developments in the theory and practice of Gastroenterology, Hepatology, diagnosis, and treatment, antibiotics, and resistance.

Using PUBTEXTO's open-access platform, scholars and doctors can get the latest information on the latest scientific developments, applications, and data interpretation in clinical and preclinical research. In addition to providing original articles, reviews, and case reports on the latest discoveries and developments related to all areas of medicine, Pubtexto is committed to bringing comprehensive and reliable information on the latest developments. Researchers can use Pubtexto to share their innovative ideas and work and to recognize their scholarly works. In this knowledge dissemination process, students, librarians, scholars, research centers, educational institutions and research centers get the most significant benefit.

JCGHR's goal is to provide the most complete and reliable source of information on the latest discoveries and developments. We encourage the submission of manuscripts that meet the general criteria of significance and scientific excellence. JCGHR journal seeks to publish a balanced mix of high-quality theoretical or Empirical research articles, Reviews, Case reports, Editorial, short communication, Letter to the editor, Commentary, book reviews, etc.,

Review Process: Double-blinded peer review process

Plagiarism Policy

The articles submitted by authors must contain a minimum of 80% unique content (Which should be unique and must not copy from any other websites). The authors must maintain 100% uniqueness in the Results and conclusion part of the text. We will resend the articles, which have below 80% uniqueness to the authors for revision and ask for resubmissions with uniqueness (as per guidelines).

Authors are welcome to submit their manuscript online at Submit Manuscript Or as an email attachment to editorjcghr2018@gmail.com

The main aim of the journal is to provide further understanding and insight into disease mechanisms and new therapies related to gastroenterology and hepatology. Topics of interest include but are not limited to the following: Gastroenterology- Endoscopy- Inflammatory bowel disease- Pancreatic disease- Celiac disease- Gastrointestinal motility- Hepatology- Hepatocellular carcinoma- Chronic hepatitis- Viral hepatitis- Cirrhosis- Liver disease- Partial Hepatectomy- Schistosomiasis- Appendicitis- Peritonitis- Colon Polyps- Constipation.

We encourage researchers, and other clinical and health professionals Worldwide to submit their manuscripts describing their original basic or clinical research findings and new diagnostic techniques to the Journal of Clinical Gastroenterology and Hepatology Research.

Gastroenterology

Gastroenterology is the branch of medicine which deals with the study of digestive system and diseases of the related organs. It involves detailed understanding of the physiology and functioning of the gastrointestinal organs. Diseases affecting gastrointestinal tract are the major focus of Gastroenterology. Hepatology is the study of liver, pancreas and biliary tract are considered as sub-specialty in this study.

Hepatology

Hepatology is the sub specialty in Gastroenterology which deals with the study, analysis, prevention and administration of ailments that influence Liver. Liver is the vital organ which plays a major role in metabolism. Liver is highly specialized and regulates a wide range of high volume biochemical reactions. Liver weighs about 1.44-1.66 kgs located at upper right quadrant of abdominal cavity and rests below diaphragm to the right of the stomach and overlies the gallbladder.

Gastric Cancer

The third most common cause of cancer-related death globally is gastric cancer, which remains difficult to treat in Western countries, mainly because most patients present with advanced disease. Cancers of the abdomen are the fifteenth most prevalent in the USA. The abdomen begins at the internal organ junction and ends at the small intestine. Almost all viscus cancers are adenocarcinomas (cancers that begin in cells that secrete mucous and produce other fluids). Alternative types of viscus cancer ar duct neoplasm tumors, duct stromal tumors, and lymphomas. Infection with a microorganism known as H. pylori may be a common reason for viscus cancer.

Endoscopy

Endoscopy is a procedure that looks inside your stomach. It uses an instrument called an endoscope, or scope for short. Scopes have a camera attached to a long, thin tube. The doctor moves it through a body passageway or opening to see inside an organ. Sometimes scopes are used for surgery, such as for removing polyps from the colon.

Gastrointestinal Surgery

The digestive system is a complex mechanism that can be harmed by illness, poor food, and psychological stress. While some digestive issues can be treated with medication and dietary adjustments, others need for surgery. The body needs the digestive system to help it digest and assimilate meals. The mouth, oesophagus, stomach, small intestine, large intestine, also known as the colon, rectum, and anus are all parts of the gastrointestinal (GI) system.

Gastrointestinal Pharmacology

Diseases of the digestive tract that need medicine management, sometimes together with different treatments, square measure peptic ulcers (omeprazole and others), hurting (laxatives, analgesics), looseness of the bowels (antibiotics, protectants and absorbents, glucocorticoids, motility inhibitors), reperfusion injury, operative enteropathy (prokinetic drugs), and adhesions. There's growing proof that nonsteroidal anti-inflammatory drug medicine will alter vital physiological properties of the intestine; but, these medicine square measure valuable medicines for horses and their use ought to be tempered with an awareness of their harmful effects.

Gastrointestinal Bleeding

Acute gastrointestinal bleeding is still a standard reason for hospitalization for abdominal emergencies. UGIB is hemorrhage originating from a supply proximal to the ligament of Treitz. Hemorrhages in the upper GI tract originate in the passageway, stomach, or small intestine (first segment of the tiny intestine). Higher GI hemorrhage is most commonly caused by: a. Peptic ulcers b. Gastritis.

Gastrointestinal Inflammation

The term inflammatory bowel disease (IBD) describes a group of disorders in which the intestines become inflamed. The most likely cause is an immune reaction against its own intestinal tissue. Two major types of IBD are ulcerative colitis and Crohn's disease. There are other, less common types of IBD called collagenous colitis and lymphocytic colitis. The inflammation can only be seen using a microscope, and is known as microscopic colitis.

Digestive Enzymes

Digestive enzymes are found within the organic process tracts of animals and humans and within the traps of carnivorous plants. They aid food digestion, similarly as within cells, particularly in their lysosomes, wherever they perform to keep up cellular survival. Digestive enzymes are diverse and are found in the saliva secreted by the salivary glands, in the stomach secreted by cells lining the stomach, in the pancreatic juice secreted by pancreatic exocrine cells, and in the intestinal (small and large) secretions, or as part of the gastrointestinal tract lining.

Gastrointestinal Hormones

GI hormones are chemical messengers that regulate several physiological functions of the canal, including secretion, absorption and digestion, and gut motility. GI hormones are an enlarged family of peptides secreted by endocrine cells found throughout the GI tissue layer and exocrine gland. Gastrin, secretin, and cholecystokinin (CCK) were the primary discovered gut hormones, and as of nowadays, there are over fifty gut internal secretion genes and a large number of bioactive peptides.

Intestinal Blockage

When there is no passageway for food or digested food to move through the bowel or intestine, an obstruction occurs. It can happen anywhere in the small or large intestine, and it can be partial or complete. Intestinal obstruction occurs when you’re tiny or gut is obstructed. The obstruction prevents fluid or digestible food from passing through. The blockage can also be partial or complete.

Epigastric Pain

Epigastric pain is pain that is restricted to the upper abdomen, just below the ribs. People who have experienced this type of pain frequently feel it throughout or immediately after consumption, or if they lie early on during consumption. It is a common symptom of gastroesophageal reflux disease (GERD). It is likely caused by stomach contents moving upward into the back of the throat, causing inflammation and burning pain.

Gall Bladder

Essentially, the bladder is a pear-shaped pouch that houses the bile (a liquid created by the liver to assist digest fatty foods). Nonetheless, the person will feel discomfort if one of the bile ducts—the tubes that carry bile from the liver to the bladder and from the bladder to the epithelial duct-becomes blocked with sludge or gallstones, infected, or irritated. Many ailments are connected to bladder pain.

Gastrointestinal Radiology

The throat, oesophagus, stomach, duodenum, intestine, colon, and biliary system are among the organs image investigations of the tract are performed and interpreted by radiologists in the channel's Radiology Section. Esophagram, upper gastrointestinal series, small internal organ series, enteroclysis, and both a regular and air-contrast enema are some of the specific procedures carried out. During this portion, plain abdominal films are taken.

Before submission of manuscript to the journal, kindly check the below mentioned guidelines

Authors Information

All persons who qualify for authorship should be listed as authors. However, the corresponding author must ensure that each author listed has substantially contributed or participated sufficiently in the work and is responsible for that particular portion of the manuscript. However, people who do not qualify for authorship should be listed in acknowledgments.

• First name and last name
• Complete affiliation, along with the country
• E-mail address (mandatory for the corresponding author)

Submission Format

Submissions to Pubtexto journals should include the following:

• Cover Letter
• Manuscript
• Figures and Tables
• Supplemental Materials

Authors are encouraged to submit all the components as 'zip file' while submitting on our online system or via email as an attachment.

Cover Letter should:

• briefly summarize or provide an outline of your manuscript, and why it is a worthy contribution to the concerned journal;
• specify the Pubtexto journal that your manuscript best pertains to;
• indicate, if applicable, that it is submitted as a part of Special Issue;
• Specify the manuscript type (original research, review, etc.)
• detail any previous interaction(s) with Pubtexto Publications (previously submitted)
• specify all authors information, including affiliation
• include acknowledgments and funding information (if applicable) and any competing interests

Manuscript Layout

The word count for original research is 3500-4000 words and up to 5500 words for studies involving meta-analysis. Authors are encouraged to employ a standard and concise writing style. If you are not a native English speaker, we encourage you to utilize our language editing services-or ask a native English speaking colleague for assistance.

Title: The title should not exceed 200 characters and set in title case. The title should be concise, specific, and easily comprehensible to readers.

Abstract: The abstract should not exceed 300 words and may or may not be unstructured (without sub-heading such as objective, methodology, results, discussion, etc.). It should provide a clear description of the objective(s) of the study, demonstrate the methodology used, and summarize the study's prime conclusion(s). In the end, a statement regarding the study\'s significance to a potentially wider audience should be included.

Keywords: Authors can provide 4-6 keywords. The first letter of each keyword should be upper case, and keywords should be separated by a semicolon (;)

Main Text

Introduction

The introduction should set the tone of the paper by providing a clear statement of the study, the relevant literature on the study subject and the proposed approach or solution. The introduction should be general enough to attract a reader\'s attention from a broad range of scientific disciplines.

Materials and methods

This section should provide a complete overview of the design of the study. Detailed descriptions of materials or participants, comparisons, interventions, and types of analysis should be mentioned. However, only new procedures should be described in detail; previously published procedures should be cited and important modifications of published procedures should be mentioned briefly. Capitalize trade names and include the manufacturer's name and address.

Results and Discussion

The results section should provide complete details of the experiment that are required to support the conclusion of the study. The results should be written in the past tense when describing findings in the authors' experiments. Previously published findings should be written in the present tense. Results and discussion may be combined or in a separate section. Speculation and detailed interpretation of data should not be included in the results but should be put into the discussion section.

Conclusion:

This section should provide to adhere to support the study conclusions. This section included briefly detailed conclusive parameters of the whole study.

Acknowledgments:

This should include all the people who have contributed toward the work in one way or the other. However, authors are required to ensure that people acknowledged should agree to be so named.

Funding Information

List all the sources of funding, including relevant research grant numbers, as applicable. Also, authors are encouraged to list all the contributing authors associated with specific funding, if applicable.

Optional information

While we are not obligated to use these or recommend to the concerned Editor(s), we do encourage authors to provide names and contact information of 2-4 external reviewers and, if applicable, 1-2 opposed reviewers.

References

Published work along with any citable items should be cited in the reference list. While we follow very stringent reference formats, authors need not to spend time formatting their reference. They can submit the manuscripts formatted in any reference style (style will be formatted once the manuscript is accepted for publication), but it is preferable that they adhere to the journal format.

Reference format:

Pubtexto uses the following style. Items are listed numerically in the order they are cited in the text.

Example journal article (2-6 authors): Salwachter AR, Freischlag JA, Sawyer RG, Sanfey HA, Fukushima H, Cureoglu. The training needs and priorities of male and female surgeons and their trainees. J Am Coll Surg. 2005; 201: 199-205.

Example journal article (more than 6 authors): Fukushima H, Cureoglu S, Schachern P, et al. Cochlear changes in patients with type 1 diabetes mellitus. Otolaryngol Head Neck Surg. 2005; 133: 100-6.

Example book: Modlin J, Jenkins P. Decision Analysis in Planning for a Polio Outbreak in the United States. San Francisco, CA: Pediatric Academic Societies; 2004.

Example book chapter: Solensky R. Drug allergy: desensitization and treatment of reactions to antibiotics and aspirin. In: Lockey P, ed. Allergens and Allergen Immunotherapy. 3rd Ed. New York, NY: Marcel Dekker; 2004:585-606.

Example online article: Wolf W. State's mail-order drug plan launched. Minneapolis Star Tribune. May 14, 2004:1B

Example article from any database: Calhoun D, Trimarco T, Meek R, Locasto D. Distinguishing diabetes: Differentiate between type 1 & type 2 DM. JEMS [serial online]. November 2011; 36(11):32-48. Available from: CINAHL Plus with Full Text, Ipswich, MA. Accessed February 2, 2012.

In-text citation: For referencing an article, a number is used. This is different from in-text citations in AMA-author's last name is not used. The order of numbering will be contingent on the order in which you use that reference within your paper. For example, the first article referenced will be given number one in superscript (1) followed by the second and third articles as 2,3. In the references section, the articles should appear numerically in the order they are cited within the text.

Figures and Tables

Figures and tables should be included in the main text (manuscript) to aid in the review process. However, for larger files (size exceeding 10 Mb) must always be submitted separately (should be properly mentioned in the main text, wherever applicable). 

Figure captions and legends

Figure files should be included in the main document, and not as supplemental materials. Figure caption should be preceded by the figure, while figure legends should immediately follow the figure. Figure captions should be concise (not to exceed 18 words) and set in bold type. All figures should be numbered in sequence, using Arabic numerals, for example, Figure 1, Figure 2, etc.

Table captions and legends

Tables should be cited in ascending numeric order. Each table should be preceded by a table caption (brief and specific; not to exceed 18 words), and immediately followed by table legends, if applicable, used to explain abbreviations and other supporting information about the data. Larger tables, however, can be submitted as supplemental materials.

Review Comments and Revision

Submission Instructions

While submitting a revised manuscript, the authors should include the following:

Revised manuscript (clean copy): Prepare a clean copy of your revised manuscript that does not show track changes. Rename this file as "Main Document".

Revised manuscript (marked-up copy): Include a copy of your manuscript file showing the changes you have made (track changes). Rename this file as "Manuscript with Track Changes".

Response to reviewers: Address the specific points made by each Reviewer or Editor. Include your responses to all the reviewers and editor's comments and list the changes you have made to the manuscript. Rename this file as "Response to Reviewers".

Supplementary Information

Information integral to the comprehensive understanding of the manuscript, but is either too large to be included in the main document or due to any other reason, should be submitted as support materials, such as 3-D visualizations, interactive graphics, large tables or figures, and so on. However, authors should note that normal figures and tables should not be included under supplemental materials.

Ethical Guidelines

For manuscripts reporting medical studies that involve human or animal subjects, the ethics committee that approved the study must be identified in the manuscript. For studies involving human subjects, all work must conform to the recognized standards as per the "Declaration of Helsinki". In case of any experiments involving animals, authors must provide a declaration that all measures were taken to avoid animal suffering at each stage and also must furnish a detailed description of the procedures used.

Patient Consent

In manuscripts reporting patient cases, patient anonymity must be preserved. Case reports submitted to Pubtexto Publications should conform to the International Committee of Medical Journal Editors (ICMJE) recommendations. Patient privacy should be taken care of, and personally, identifiable information should not be revealed without informed consent. If informed consent has been obtained, the details must be mentioned in the manuscript.

For live patients, signed consent is mandatory if the authors wish to reveal the patient's identity. In the case of deceased patients, consent must be taken from the patient's next of kin. If a patient's consent was not obtained, the patient's details should be anonymized as much as possible. Patient's photographs need to be cropped sufficiently to prevent the revelation of identity.

Authors are not required to submit the copy of the patient's consent while submitting their manuscript for consideration in Pubtexto Publications. However, they should confirm in the Cover Letter that the patient\'s consent has been obtained. In certain instances, the Editorial Office might request the authors to provide a copy of the same.